What code should be used to confirm cases of HIV according to ICD-10-CM coding practice?

The appropriate code to confirm cases of HIV in ICD-10-CM coding is B20. This code specifically indicates a diagnosis of HIV disease. It is used for patients who have been confirmed to have HIV and have progressed to the point of having AIDS.

Z21, on the other hand, is used for patients who are HIV positive but do not have any current symptoms or an AIDS diagnosis. R65.2 relates to systemic inflammatory response syndrome (SIRS) and does not pertain to HIV coding.

The option labeled "Confirmed" is not an ICD-10-CM code and doesn't align with the coding system structure. Therefore, while it may suggest confirmation, it does not provide the standardized code required for documenting an HIV diagnosis.